Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody

BPRC - 1. Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody

We have recently reported a new method for testing the effectivity of new immunotherapies for multiple sclerosis using magnetic resonance imaging techniques in marmosets, thereby quantifying the activity of lesions within the brain white matter.

‘t Hart BA, Brok HP, Remarque E, Benson J, Treacy G, Amor S, Hintzen RQ, Laman JD, Bauer J, Blezer EL: Suppression of ongoing disease in a nonhuman primate model of multiple sclerosis by a human-anti-human IL-12p40 antibody.
J Immunol. 2005 Oct 1;175(7):4761-8. (PubMed)