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In total there are 168 English news articles.
As research institute, BPRC takes its responsibility to inform the rest of the world about its activities serious. For example, visitors days are organised.
The development of a vaccine against HIV is complex, because the virus is constantly changing its composition. After all, a vaccine must be effective against all strains. To circumvent this problem, a vaccine has been developed which is directed against parts of the virus that remain constant. In monkeys it was studied whether this vaccine could confer protection against the virus.
Unfortunately, to date, it is impossible to predict the efficacy of an experimental vaccine against HIV. Animal models play an important role in the development of an anti-HIV vaccine. These models are not only important for testing the efficacy of vaccine candidates, but also provide the opportunity to explore the mechanism of protection against disease.
Prof. Dr. Ronald Bontrop, general and scientific director of the BPRC, has been invited as Raine Visiting Professor at the University of Western Australia.
Until now, little was known about the genetic variation within the great apes, due to the difficulty in obtaining samples from apes. An international group of more than 75 researchers, including BPRC staff, and conservationists have joined efforts to make a comprehensive analysis of the genetic background of these animals at the population level.
Most probably in the distant past a precursor of the HIV virus has caused high mortality among chimpanzees. Only chimpanzees with an immune system that could control the virus survived. The current chimpanzee population is descended from these ‘survivors’. Their immune system is specialized to efficiently control this type of viruses. This is in contrast to the situation in humans, where an infection with HIV almost always will cause AIDS.
The discussion on the use of primates in biomedical research and the importance of ensuring optimal animal welfare is discussed in Public Service Review ((European Science & Technology) 17 and in Science Omega Review Europe, issue 1.
Parkinson’s disease is a disorder of the central nerve system, due to a progressive loss of a specific type of nerve cells (dopamine neurons) that govern the control of movement. This situation can be mimiced in marmosets, offering the opportunity to explore new treatments for this widespread disease.
To date, there are only a handful of drugs available against malaria. Moreover, resistance to these drugs is rapidly emerging and new drugs are therefore urgently needed. Recent research has identified a promising new class of anti-malarial compounds.