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In total there are 168 English news articles.
On 23 May 2012 Anwar Jagessar successfully defended his thesis entitled "Mechanistic refinement of the common marmoset model for multiple sclerosis"
New drugs against malaria are urgently needed, since resistance against all currently available drugs has been shown. In the leading journal PNAS a new development is reported: a new generation of compounds has been discovered that can attack the parasite at two compartments.
Recombination is an important process in biology. During this process DNA of the parents is exchanged generating a unique combination of DNA in the children. In the absence of this process we would all be equal at DNA level. A natural selection takes place in which benificial combinations remain in the population.
On 6 March 2012 at Groningen University, Prof. Dr. Bert ‘t Hart held his inaugural speech entitled: ‘Multiple Sclerosis, a progressive problem’.
New tools to study the genetic origin of chimpanzees: the existence of a fourth genetically distinct chimpanzee population
Chimpanzees are viewed with fondness as our closest animal relatives and are valued by scientists for the biological and evolutionary insights they provide. In spite of this, the relationships between different populations of common chimpanzees are still relatively poorly understood, a situation that potentially threatens conservation efforts.
Protection of HIV-1 vaccinated rhesus macaques can be predicted in vitro by the speed at which virus is neutralised by rhesus antibodies
In the search towards an HIV vaccine it is important to test the level of protection against a vaccine. This can not be done in humans and therefore research in monkeys can provide a way ahead. Rhesus monkeys can be immunised with human vaccine candidates and subsequently the level of protection provided by the vaccine candidates can be determined after infection of the animals with an adapted variant of HIV. Neutralising antibodies can protect against HIV through inactivation of the virus. The mode of action of the neutralising antibodies can be assessed by various in vitro tests.
On 18 January 2012 Kwadwo Kusi successfully defended his thesis entitled ‘Towards a blood stage malaria vaccine; dealing with allelic polymorphism in the vaccine candidate apical membrane antigen 1’.
Malaria infected red blood cells can bind to the small blood vessels inside various organs. In humans, the malaria parasite Plasmodium falciparum causes severe disease because this sequestration can lead to malfunctioning of the affected organs and coma in case the brain is affected. Therapeutic interventions to avoid this sequestration are currently being investigated, but the consequences of disrupting sequestration are unknown, since this can not be studied in humans.
On November 4 and 5 2011, the first joint meeting between EUPRIM-NET (Network activity 2) and the EPV was held at the BPRC.
In the popular journal Elsevier (5 November 2011) the new building of the BPRC is highlighted.