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In total there are 165 English news articles.
Leading scientific journals such as Science and Nature, draw the attention of scientists to studies published elsewhere that have provided important scientific insights.
Pluripotent stem cells: new opportunities for therapies against multiple sclerosis (MS) tested in a monkey model for MS
The disease MS is a disorder of the central nervous system. Current therapies focus on delaying the disease; it is not yet possible to cure the disease. The development of new technologies offers new opportunities. In close collaboration with BPRC scientists, research groups from the Netherlands and abroad have for the first time explored the application of such an innovative technology in monkeys: the use of induced pluripotent stem cells to repair nerve damage.
Infection with Epstein Barr Virus (EBV) is a major risk factor for the development of multiple sclerosis (MS). However, it is not clear why this is the case. Using monkey models, BPRC researchers claim to have found a possible explanation for this association.
On 8 June 2016 Saskia Burm successfully defended her thesis entitled ‘Inflammasome-mediated activation of microglia’.
IL-1β, an important protein for the development of MS, is mainly produced in the central nervous system itself
In the search for new therapies for multiple sclerosis (MS), it is important to understand which substances play a role in the onset and the development of the disease. Research on brain tissue from MS patients and rhesus monkeys with EAE (Experimental Autoimmune Encephalomyelitis) as an animal model for MS has provided new insights.
On 10 May 2016 Sigrid Franke successfully defended her thesis ‘A slow progressive marmoset model for idiopathic Parkinsons’s disease’.
Parkinson's disease (PD) is, next to Alzheimer's disease, the second most common progressive neurodegenerative disorder of the brain. Although age is the most important risk factor to develop PD, little is known about the cause of this disease. Multiple factors may play a role in the pathology of this disease. However, not everyone will develop PD in life. In a small part of the patients genetic factors will play a role, but from most patients the cause of the higher susceptibility is still unknown.
More than half of the malaria cases outside Africa is caused by the malaria parasite Plasmodium vivax. A complication in the treatment is the presence of dormant stages in the liver that after weeks to years can cause a new malaria attack in the blood and thereby disease. There is a single drug available that is only effective after a long treatment regime. This drug has serious side effects in large groups of people. Therefore more research is needed to develop new treatments against these dormant parasite stages.
Five male long-tailed macaques that entered the Netherlands as stowaway on a freighter were placed permantly at the BPRC by the Ministry of Economic Affairs. This Ministry is responsible for animal welfare issues. The BPRC is a scientific institute which offers spacious animal enclosures where animals are socially housed.
The human genetic code can provide valuable insights into the evolution of humans. Comparing the human genetic code to that of apes and monkeys may help to unravel the evolutionary history of man.