News

Page 5 of 17.
In total there are 165 English news articles.

22 February 2016
PhD awarded to Babs Verstrepen at Erasmus University Rotterdam

PhD awarded to Babs Verstrepen at Erasmus University Rotterdam


On 18 February 2016 Babs Verstrepen successfully defended her thesis "Chronic hepatitis C virus infection in chimpanzees - prevention and consequences."

2 February 2016
Participation of the BPRC in a new consortium for the development of an AIDS vaccine

Participation of the BPRC in a new consortium for the development of an AIDS vaccine


Although there has been enormous progress in the prevention and treatment of HIV/AIDS, worldwide still 35 million people are infected with HIV with ca. 6,000 new infections each day. Therefore, a vaccine is still desperately needed.

1 February 2016
ALTERNATIVES FOR ANIMAL STUDIES: BPRC PARTICIPATES IN EUROPEAN PROJECT

ALTERNATIVES FOR ANIMAL STUDIES: BPRC PARTICIPATES IN EUROPEAN PROJECT


BPRC is involved in a new European research project on replacement of animal studies for vaccine batch testing.

6 January 2016
Complex expression patterns in parts of orangutan DNA that are important for the immune system

Complex expression patterns in parts of orangutan DNA that are important for the immune system


The Major Histocompatibility Complex (MHC) is a highly complex system, which plays an important role in the recognition of pathogens. This system exhibits a high degree of variation in order to prevent elimination of an entire population by a single pathogen. A component of the MHC, the MHC class I, plays a central role in responses of the immune system against infections and cancer.

29 December 2015
Manipulation of the immune system by the tubercle bacillus

Manipulation of the immune system by the tubercle bacillus


Annually, TB kills about 1.5 million people. Improved diagnostics and tools to monitor treatment effects would significantly enhance effectiveness of TB therapies.

28 December 2015
Parkinsonian symptoms in marmosets without permanent damage to body cells

Parkinsonian symptoms in marmosets without permanent damage to body cells


In 1982, it was observed that MPTP, a by-product of the drug MPPP, caused early parkinsonian symptoms in drug users who had used drugs contaminated with MPTP. It is unknown how MPTP causes these symptoms. Nowadays, MPTP is used in research on Parkinson's disease.

28 December 2015
Correlation between virus production and the development of a functional immune response

Correlation between virus production and the development of a functional immune response


The immune system and the physiology of rhesus and cynomolgus monkeys is very similar to that of humans. Therefore, these animals play an important role in research on the safety and efficacy of new influenza vaccines.

9 December 2015
BPRC’s TB researchers team up with the global Collaboration for TB Vaccine Discovery

BPRC’s TB researchers team up with the global Collaboration for TB Vaccine Discovery


BPRC has been selected as one of the expert centres for the “Collaboration for Tuberculosis Vaccine Discovery” that was recently initiated by the Bill & Melinda Gates Foundation.

24 September 2015
What happens to chimpanzees after infection with the chimpanzee-AIDS virus?

What happens to chimpanzees after infection with the chimpanzee-AIDS virus?


The HIV/AIDS pandemic originates from cross-species transmission of the AIDS virus from chimpanzees to humans. Many African monkeys are infected with SIV, but those studied in captivity generally do not develop disease. However, wild chimpanzees infected with the chimpanzee-AIDS virus are at increased risk of death and may develop an AIDS-like disease. Is this because they live in the wild, or is it due to differences between simian AIDS viruses and chimpanzee and human AIDS viruses?

16 September 2015
Immune recognition: how do monkeys cope with pathogens?

Immune recognition: how do monkeys cope with pathogens?


Many pathogens that cause disease in humans, can also cause disease in (rhesus) monkeys and therefore monkeys play an important role as a model-species in the search for cures against these diseases. A lot of therapies involve the stimulation of the immune system in order to eliminate the presence of the pathogens. As a consequence, knowledge of the immune system of monkeys is important for this type of work. This may also aid in the selection of a minimal number of animals for experimental purposes.

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