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In total there are 168 English news articles.
Viruses can skip from monkeys to humans. The reverse situation can also occur. For health benefit of man and ape, it is important to investigate these potentially dangerous viruses.
Because of their close resemblance to humans, non-human primates (NHP) are used to study particular aspects of human biology and disease. That resemblance also poses an important dilemma in biomedical research. Like humans, non-human primates are complex social species and their welfare, housing and care taking is demanding for specialized expertise and facilities. Both society and biomedical researchers wish to reduce the numbers of animals needed for experimental purposes to an absolute minimum, with a maximum effort to ensure animal welfare and good science. Important guidelines for that quest are the three R’s of Replacement, Reduction and Refinement.
The malaria parasite Plasmodium vivax, worldwide one of the most common causes of malaria in humans, can hide in the liver for years and, following an unknown trigger, cause disease. These dormant forms, called hypnozoites, are difficult to eliminate. Due to the inaccessibility of this stage of the parasite life cycle, very little is known about the biology of hypnozoites. As a result, drug targets for new treatment regimes that eliminate these stages are lacking. Therefore, the development of a culture system that enables research on the awakening of hypnozoites is very welcome.
At the end of 2013, around 30 participants from all over Europe gathered for a workshop on Primate Welfare and Enrichment at the BPRC. This workshop was co-hosted by the EU programme EUPRIM-Net and by AnimalConcepts and focused on improving animal welfare through training and enrichment.
To date, there is no vaccine available against malaria. Therefore, research efforts are directed towards finding a weak spot of the parasite that could be developed into a new vaccine candidate. BPRC researchers were closely involved in the identification, characterization and production of AMA-1, a protein that is essential for the parasite. Years of research have now resulted in the first tests of an optimized version of the molecule in humans.
What can we learn from monkey behaviour? Can monkey behaviour explain something about our own social behaviour? Do monkeys have the capacity to think? Prof. Dr. Liesbeth Sterck hopes to find answers to these questions. On Wednesday January 22 2014, she held her inaugural speech ‘Chillen op de apenrots’.
The malaria parasite Plasmodium vivax (P. vivax ) is one of the most frequent causes of (severe) malaria worldwide. Technically it is very difficult to perform experiments with P. vivax, due to the inaccessibility of some of its developmental forms. A culture system with monkey malaria parasites and monkey cells offers the opportunity to overcome these issues.
Ronald Bontrop, director of the BPRC, is the Van Loghem Laureate 2013 and presented the prestigious Van Loghem lecture at the annual symposium of the Dutch Society for Immunology (NVvI) in Noordwijkerhout on 18 and 19 December.
Each year, the infuenza virus causes severe illness in millions of people worldwide. Unfortunately, the virus mutates very rapidly and unpredictable. Therefore, the current flu vaccines do not always provide full protection against flu.
New drugs are urgently needed in the fight against malaria because the parasite is becoming resistant against existing anti-malarials. For the development of new drugs, it is very important to identify its target, because it often reveals a parasitic Achilles heel. Recently, a previously unknown weak spot has been identified in the malaria parasite.