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In total there are 163 English news articles.
Plasmodium cynomolgi (P. cynomolgi) is closely related to the people malaria parasite Plasmodium vivax. This parasite causes each year millions of serious illnesses in endemic areas.
The development of an efficacious HIV-1 vaccine remains a global priority to prevent new cases of HIV-1 infection. Of the six HIV-1 efficacy trials to date, only one has demonstrated partial efficacy, and the immune correlates analysis of this trial revealed a role for binding antibodies and antibody Fc mediated effector functions.
The MHC system plays a central role in the recognition of pathogens. Most genes of the MHC system in humans and monkeys are very variable and can especially in Old World apes, such as macaques, occur in different numbers. Therefore, when testing new therapies for diseases in experimental animals it is important to know the variability and numbers of MHC genes of these animals.
MHC class I molecules play a central role in the defense of viruses. The study of the DNA that encodes the MHC can teach us a lot about the effects of pathogens on our immune system.
There are indications that partner choice of people is unconsciously focused on ensuring a progeny that is well-armed against pathogens. The Major Histocompatibility Complex (MHC) is a component of the immunesystem which plays an important role in the recognition of pathogens.
Despite all the research effort to target neurodegeneration, there is still a lack of satisfactory drug-mediated treatments for Parkinson´s disease. Therefore, there is an urgent need for new treatment modalities such as neurofeedback technology that target diseases of the brain. Neurofeedback is based on neurological compensatory mechanisms that help our brain to adjust to ever-changing conditions, including Parkinson´s disease.
A renewed and improved database for the genes of the major histocompatibility complex of different animal species
Our body must recognize viruses, bacteria and parasites and distinguish these from its tissues to render the pathogens harmless without attacking the own tissues. A very complex part of the immune system is responsible for this, the major histocompatibility complex (MHC).
We are pleased to present the BPRC 2016 Annual Scientific Report
BPRC researchers have previously shown that an EBV-related virus can disrupt the immune system of monkeys and can therebye cause multiple sclerosis (MS) (http://www.bprc.nl/en/article/infection-with-a-virus-related-to-epstein-barr-dysregulates-the-immune-system-of-monkeys). This work has been described previously in the Multiple Sclerosis Journal - Experimental, Translational and Clinical
Each cell in the body contains the same DNA, the genetic code that determines which proteins may be produced by a cell. However, the proteins that are produced differ significantly between cells of different tissues. Similarly, the timing of expression and the expression levels are regulated in a complex manner at different levels. For example, certain molecules such as methyl groups can bind to specific parts of the DNA. Such genetic modification often leads to suppression of the transcription of the gene and the associated protein production.